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Francoise Adan, MD, ABIHM, Director of Connor Integrative Health Network, University Hospitals. Burnout and compassion fatigue are serious concerns for caregivers across the healthcare industry and we are seeing their effects now more than ever before. To respond to the additional professional and personal stressors, losses, and challenges caused by the COVID-19 pandemic, University Hospitals (UH) developed a resilience program—UH4YOU—for the entirety of its workforce, with the Chief Human Resources Officer as the program’s executive champion. UH4YOU provides compassionate support and practical resources to all UH employees during COVID-19 and beyond. A key factor in the program’s success has been a strategic change in communication tone, including a daily Self-Care Toolbox message filled with resources, tips, and positive news designed to help employees feel uplifted and supported in this time of uncertainty. Dr. Adan shares the successes, challenges, and lessons learned during the planning and implementation of this valuable program.